599995精准一码 599995精准一码

About

Leadership Scientific Advisory Board Locations Development History Awards
About us

Apeloa, founded in 1989, is a publicly traded company as part of the Hengdian Group. Headquartered in Hengdian, Zhejiang, Apeloa has over 7,000 employees worldwide. Apeloa is China's top 2 exporter of APIs and the top 5 CDMO companies. It also ranks 36th among China’s pharmaceutical companies.

Apeloa’s core businesses include API, CDMO, FDF, and ACI, with seven API manufacturing sites (five chemical synthesis and two fermentation) and two drug product sites. Our products cover cardiovascular, anti-infection, psychotropic, and anti-cancer treatments, with production bases in Zhejiang, Shandong, and Anhui. Since 2007, our main API manufacturing sites have passed audits by NMPA, US FDA, EMEA, and PMDA, establishing us as a leading API enterprise. Our CDMO business maintains strategic partnerships with top pharmaceutical companies globally, offering comprehensive services and sustaining high growth. Apeloa’s brands, "Baishixin" and "Tianliwei," have been widely recognized, and our first extended-release product has successfully entered the U.S. market.

Apleoa implements the development strategy of "Global API Leader, CDMO Excellence, High-quality & Affordable Medicine, Expanding Aesthetic & Care Ingredients", with annual R&D expenses exceeding 5% of revenue. We support leading technology platforms with over 1,300 scientists and collaborations with top universities. Our philosophy emphasizes technology driven, high-standard compliance, and cost efficiency, aiming to be a global leading technology-driven pharmaceutical manufacturer.

36

Top 36 Chinese pharmaceutical industry enterprises

2

Ranked 2nd in the Country for the Export of Chemical API

5

Top 5 Small Molecule CDMO Companies in China

1300 +

R&D Team of More Than 1,200 People

599995精准一码 599995精准一码

Mission

Technology for Health

599995精准一码 599995精准一码

Vision

To Be a Global Leading Technology-Driven Pharmaceutical Manufacturer

Leadership
599995精准一码

Mr. Fangmeng Zhu (Brian Zhu), Holds a master degree, a CEIBS EMBA, a senior engineer and economist, joined Apeloa in 1997 and has more than 20 years of experience in the pharmaceutical industry, who is the current chairman and CEO of Apeloa.

Fangmeng (Brian) Zhu

Chairman & CEO

599995精准一码

Mr. Xinliang Xu, holds a CEIBS EMBA, is a senior engineer, joined Apeloa in 1992 and has more than 30 years working experience in the pharmaceutical and chemical industry, and he is the vice chairman of Apeloa.

Xinliang Xu

Vice Chairman

599995精准一码

Mr. Chun He, holds a CEIBS EMBA, is a senior engineer, joined Apeloa in 1998 and he is the president of Apeloa.

Chun He

President & Head of ACI BU

599995精准一码

Mr. Min Jin, holds a CEIBS EMBA, is a senior economist, has more than 20 years experience in pharmaceutical and chemical industry. He is the SVP.

Min Jin

Senior Vice President

599995精准一码

Mr. Lei Cai (George Cai), holds a master degree, a CEIBS EMBA. He is the Corporate VP, head of CDMO BU of Apeloa.

Lei (George) Cai

Corporate Vice President & Head of CDMO BU

599995精准一码

Mr. Yuwang Zhou, Economist. In August 2003, he obtained the certificate of Secretary of the Board of Directors of listed companies issued by the Shenzhen Stock Exchange.

Yuwang Zhou

Vice President & Secretary of the Board

599995精准一码

Mr. Jinhui Zhang, has a master degree and is a senior accountant.

Jinhui Zhang

CFO

599995精准一码

Mr. Qing Chen, is a senior engineer.

Qing Chen

Assistant President

599995精准一码

Mr. Yonglong Li (Ray Li) , holds a master degree, a CEIBS EMBA in progress. He is head of API BU of Apeloa.

Yonglong (Ray) Li

Head of API BU

599995精准一码

Mr. Liang Yu, is head of FDF BU of Apeloa and has rich experience in R&D and sales.a CEIBS EMBA in progress.

Liang Yu

Head of FDF BU

Scientific advisory board

Apeloa Scientific Advisory Board established in December 2022, abbreviated as "ASAB". The ASAB is dedicated to providing strategic direction and planning advice for the company, participating in the initiation and evaluation of major projects, and the recruitment and development of key talents. It offers recommendations on the adoption and application of advanced technologies, enhancing the professionalism and scientific rigor of Apeloa's strategic decision-making. This will propel Apeloa to the forefront of biomedical manufacturing technology both domestically and internationally, helping it to become a leading technology-driven pharmaceutical manufacturing company in China.

The inaugural ASAB is composed of five renowned experts in the field of biomedicine, specializing in areas such as organic chemical synthesis, synthetic biology, biomanufacturing engineering technology, chemical engineering and microfluidic technology, pharmaceutical engineering and processes, and drug molecular design and process development.

599995精准一码

Ma Shengming Ph.D

Academician of the Chinese Academy of Sciences; Fellow of the Academy of Sciences for Developing Countries (TWAS); Professor at Fudan University; Expert in organic chemistry and metal-catalyzed reactions
599995精准一码

Zheng Yuguo Ph.D

Academician of the Chinese Academy of Engineering; Dean at Zhejiang University of Technology; innovator in biomanufacturing engineering
599995精准一码

Li Ang Ph.D

Deputy Director at the Shanghai Institute of Organic Chemistry; specialist in total synthesis of complex natural products
599995精准一码

Xu Jianhong Ph.D

Professor at Tsinghua University; authority on microchemical processes and multiphase microfluidic technology
599995精准一码

Du Zhengming Ph.D

Former Senior Vice President of BeiGene; Expert in small molecule drug development and pharmaceutical R&D management
599995精准一码

Locations
China
USA
Germany
Japan
599995精准一码

599995精准一码
Hengdian, Zhejiang

Apeloa Pharmaceutical Co., Ltd.

Add:399 Jiangnan Road, Hengdian, Dongyang, Zhejiang 322118, China

Apeloa Headquarter

Functional Management Service Centre

599995精准一码

599995精准一码
Hengdian, Zhejiang

Apeloa API R&D Center

Add:368 Jiangnan Second Road, Hengdian, Dongyang, Zhejiang 322118, China

5,400 square meters

Research and technical improvement for APIs and Intermediates

Crystallization & Particle Engineering and Synthetic Biology & Biocatalysis technology platform

599995精准一码

599995精准一码
Hengdian, Zhejiang

Apeloa CDMO (Hengdian) R & D Center

Add:368 Jiangnan Second Road, Hengdian, Dongyang, Zhejiang 322118, China

8,200 square meters

Capacity for 500+ R&D personnel

Process development/optimization/CMC

Technology platform (Peptide, high potency and flow chemistry)

599995精准一码

599995精准一码
Hengdian, Zhejiang

Zhejiang Apeloa Tospo Pharmaceutical Co., Ltd.

Add:519 Jiangnan Road, Hengdian, Dongyang, Zhejiang 322118, China

140,000 square meters

Clinical/commercial API manufacturing services

Passed USFDA and PMDA inspection

599995精准一码

599995精准一码
Hengdian, Zhejiang

Zhejiang Apeloa Jiayuan Pharmaceutical Co., Ltd.

Add:368 Jiangnan Second Road, Hengdian, Dongyang, Zhejiang 322118, China

250,533 square meters

Pre-clinical, clinical/commercial API manufacturing services

Passed USFDA and PMDA inspection

599995精准一码

599995精准一码
Hengdian, Zhejiang

Zhejiang Apeloa Kangyu Pharmaceutical Co., Ltd.

Add:333 Jiangnan Road, Hengdian, Dongyang, Zhejiang 322118, China

460,000 square meters

Pre-clinical, Clinical/commercial API and drug product manufacturing services

Passed USFDA and PMDA inspection

599995精准一码

599995精准一码
Hengdian, Zhejiang

Zhejiang Apeloa Biotechnology Co., Ltd.

Add:Geshan Industrial Zone, Dongyang, Zhejiang 322109, China

141,000 square meters

Microbial fermentation manufacturing service for API

Passed USFDA, EDQM and PMDA inspection

599995精准一码

599995精准一码
Hangzhou, Zhejiang

Hangzhou Apeloa Medicine Research Institute Co., Ltd.

Add:4-202, No. 291 Fucheng Rd. Xiasha, Jianggan, Hangzhou Zhejiang 310016, China

2,700 square meters

Research and CMC service for drug product

Innovative formulation technology platform

599995精准一码

599995精准一码
Hangzhou, Zhejiang

Zhejiang Hengdian Apeloa Imp. & Exp.Co., Ltd.

Add:13/F, T1, Hengdian Center, No. 136 Fuchun Road, Shangcheng District, Hangzhou, Zhejiang 310016, China

Top3 exporter in China (API & Intermediate)

Global business development headquarter

599995精准一码

599995精准一码
Pudong, Shanghai

Apeloa (Shanghai) Pharma Solutions Co., Ltd.

Add:No.8666, Shanghai Zhicheng Building 8, Xuanqiaozhen Hunan Highway, Pudong, Shanghai 201314, China

6,400 square meters

300+chemists

Process development/optimization/CMC

599995精准一码

599995精准一码
Quzhou, Zhejiang

Zhejiang Jutai Pharmaceutical Co., Ltd.

Add:51 Donggang Road 1st, Kecheng District,Quzhou ,Zhejiang 322118,China

Cephalosporins and penicillins production base

Covering an area of 70,000 square metres

Formulation CMO Custom Services

599995精准一码

599995精准一码
Dongzhi, Anhui

Anhui Apeloa Biotechnology Co., Ltd.

Add:Dongzhi Economic Developing Area, Anhui 247260, China

360,000 square meters

Microbial fermentation/chemical synthesis manufacturing service for API and intermediate

Passed NMPA and EDQM inspection

599995精准一码

599995精准一码
Weifang, Shandong

Shandong Apeloa Tospo Pharmaceutical Co., Ltd.

Add:Lingang Indutrial Park, Binhai Economic and Technological Development Zone, Weifang, Shandong 261000, China

293,000 square meters

Chemical synthesis manufacturing service

Manufacturing capability for challenging chemistry (Fluorination)

599995精准一码

599995精准一码
Weifang, Shandong

Shandong Apeloa Hanxing Medical Co., Ltd.

Add:Binhai (Xiaying) Economic Development Zone, Changyi, Weifang, Shandong 261000, China

350,000 square meters

Chemical synthesis manufacturing service

599995精准一码

599995精准一码
Boston

APELOA PHARMA SOLUTIONS

Add:35 Dunham Road, Billerica, MA 01821

Operational as of May 2024

1,500 square meters

Tech Development Platform

Early stage discovery/lead optimization/process development and scale-up service (GLP batch)

599995精准一码

599995精准一码
Frankfurt

APELOA Europe GmbH

Add:Friedrich-Ebert-Anlage49th/23rdfloor Frankfurt am Main, Germany 60308

Founded in Nov 2022

Business development office

A bridge between China and Europe

599995精准一码

599995精准一码
Tokyo

APELOA Japan Office

Add:7F, 6-20-2, Shinbashi, Minato-ku, Tokyo

Founded in Jan 2024

Business development office

A bridge between China and Japan

Development History

1989-2001

Start-up

2001-2017

Development

2017-Present

Expansion

599995精准一码

Start-up

1989-2001

599995精准一码

Start-up

1989.04

599995精准一码

Start-up

1991.01

599995精准一码

Start-up

1991.05

599995精准一码

Start-up

1998.10

599995精准一码

Start-up

1999.12

1989.04

Mr. Yong'an Xu, the chairman of Hengdian Group, founded Yong'an Chemical Factory in Dongyangin July 1990. It was later merged with No.1 Dongyang Organic Chemical Factory to establish Hengdian Group Yong'an Chemical General Factory, which developed into the subsidiary Apeloa Tospo Pharmaceutical.

1991.01

Hengdian Group established Dongyang Organic Synthesis Chemical Factory No. 4, which was later merged with Dongyang Organic Chemical Factory No. 6 and No. 9 to form Dongyang Organic Chemical General Factory, and subsequently developed into the subsidiary Apeloa Jiayuan Pharmaceutical.

1991.05

Hengdian Group established DongYang Pharmaceutical Chemical Factory, which later merged with Dongyang Pharmaceutical Industry Company to form Dongyang Pharmaceutical and Chemical General Corporation. Subsequently, it developed into the subsidiary Apeloa Kangyu Pharmaceutical.

1998.10

The first national class II new drug, the Ubenmus capsule, was approved by CFDA(China Food and Drug Administration).

1999.12

The first API production line passed the GMP inspection.

599995精准一码

Development

2001-2017

599995精准一码

Development

2001.11

599995精准一码

Development

2007.01

599995精准一码

Development

2012.03

2001.11

The company has completed the listing in the Chinese stock market (stock code: SZ 000739).

2007.01

Passed the FDA on-site inspection for the first time.

2012.03

The first API product passed the WHO on-site inspection, and the PMDA on-site inspection passed in November 2012.

599995精准一码

Expansion

2017-Present

599995精准一码

Expansion

2018.05

599995精准一码

Expansion

2019.05

599995精准一码

Expansion

2019.07

599995精准一码

Expansion

2019.08

599995精准一码

Expansion

2019.09

599995精准一码

Expansion

2020.03

599995精准一码

Expansion

2021.06

599995精准一码

Expansion

2021.08

599995精准一码

Expansion

2021.11

599995精准一码

Expansion

2022.12

599995精准一码

Expansion

2023.06

599995精准一码

Expansion

2023.11

2018.05

The Pharmaceutical Research Institute moved into Hangzhou Pharmaceutical Port.

2019.05

The first generic drug passed the consistency evaluation and won the bid of the national centralized procurement in September 2019.

2019.07

The CDMO R&D Center (Shanghai) was put into use.

2019.08

The first API product passed the on-site inspection by the EDQM.

2019.09

The first ANDA was approved by the US FDA.

2020.03

Synthetic biology and enzyme catalysis, flow chemistry, Crystallization & Particle Engineering, and peptide technology platforms were established.

2021.06

The first flow chemistry workshop (commercial scale) was put into use.

2021.08

In August, the CDMO R&D Center was established in Boston, USA.

2021.11

The first multi-functional CDMO workshopwas put into use and the Process Safety Center passed CNAS certification.

2022.12

The Analytical Testing Center passed the CNAS certification; the first scientific advisory committee of the company was established; the sales revenue exceeded 10 billion yuan for the first time, reaching 10.5 billion yuan.

2023.06

The first highly potent workshop was put into use.

2023.11

The Global Innovative R&D and Production Service Platform (CDMO) was completed.

Awards

2020

  • Ranked 40th among the Top 100 Pharmaceutical Industries in China in 2020
  • Top 20 Chinese CRO in 2020 (including CDMO), Top 100 in China's Pharmaceutical Industry, MENET
  • 2020 China Chemical Pharmaceutical Industry Environmental Protection, Green Pharmaceutical Ad Hoc Award

2021

  • No.44 among the Top 100 Enterprises in China's Pharmaceutical Industry in 2021
  • SFC Most Valuable Investment Company of the Year
  • MENET 2021 China CXO Enterprises TOP20 (12th) 2021 China Chemical Pharmaceutical
  • Industry Outstanding Enterprises and Outstanding Products API Export-oriented Outstanding Enterprises Brands

2022

  • The 38th of the Top 100 Enterprises in China's Pharmaceutical Industry in 2022
  • China Top 100 High Growth Enterprises Award
  • China Patent Excellence Award (a synthesis method of cefixime)
  • Top 100 Chinese Chemical Pharmaceutical Enterprises in 2022 (No. 20) by MENET

2023

  • The 36th of the Top 100 Enterprises in China's Pharmaceutical Industry in 2023
  • China Top 100 High Growth Enterprises Award
  • China Biomedical Industry Chain Innovation and Transformation Centre 2023 Influential CDMO Companies
  • Top5 Chinese CDMO Enterprises in 2023